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Symbol
Name
ID

Tnip1
TNFAIP3 interacting protein 1
MGI:1926194

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased B cell proliferation

enlarged spleen

increased spleen weight

spleen hyperplasia

anemia

increased basophil cell number

decreased erythrocyte cell number

decreased hematocrit

decreased hemoglobin content

increased mean corpuscular hemoglobin

increased mean corpuscular hemoglobin concentration

increased red blood cell distribution width

increased neutrophil cell number

increased granulocyte number

thrombocytopenia

increased mean platelet volume

increased plasmacytoid dendritic cell number

increased dendritic cell number

increased germinal center B cell number

decreased B-2 B cell number

increased B-1a cell number

increased B-1b cell number

increased plasma cell number

decreased B cell number

increased B cell number

increased T follicular helper cell number

increased memory T cell number

decreased lymphocyte cell number

increased large unstained cell number

increased macrophage cell number

increased monocyte cell number

abnormal leukocyte morphology

abnormal plasma cell morphology

abnormal effector T cell morphology

increased spleen red pulp amount

abnormal spleen germinal center morphology

increased spleen white pulp amount

increased IgA level

increased IgE level

increased IgG1 level

increased IgG2a level

increased IgG2b level

increased IgG3 level

increased IgG level

increased IgM level

increased immunoglobulin level

abnormal hematopoietic stem cell physiology

Availability

Mouse Genotype

Tnip1^{Gt(E059E05)Wrst}/Tnip1^{Gt(E059E05)Wrst}

Tnip1^m1Btlr/Tnip1^m1Btlr

Tnip1^tm1.1Ama/Tnip1^tm1.1Ama

Tnip1^tm1.1Pcoh/Tnip1^tm1.1Pcoh

Tnip1^{tm1b(EUCOMM)Hmgu}/Tnip1^{tm1b(EUCOMM)Hmgu}

Tnip1^tm1.2Ama/Tnip1^tm1.2Ama
Tg(Itgax-cre)1-1Reiz/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23